Best endpoint protection software tools for MSPs in 2026

MSPs need endpoint protection software tools with multi-tenant architecture, flexible per-client or per-technician pricing, PSA and ticketing integration, white-label options, and NOC-grade alerting that scales across hundreds of client environments without multiplying admin overhead.

15 tools in this category.

All endpoint protection software tools

These tools are part of the endpoint protection software category but may not match the for msps filter above. Worth reviewing if the primary options don't fit.

BigFix logo

BigFix

Custom quote · Cloud / On-prem

BigFix is positioned here as a endpoint management software option for teams comparing rollout fit, operating model, pricing structure, and how much administrative effort the product is likely to create after implementation.

View profileContact vendor for exact pricing and packaging details.
Bitdefender GravityZone logo

Bitdefender GravityZone

Custom quote · Cloud / On-prem · Free trial

Bitdefender GravityZone offers the best detection-to-price ratio in endpoint protection — consistently strong independent test results at 40-60% less than CrowdStrike — making it the top value pick for mid-market.

View profileContact vendor for exact pricing and packaging details.
CrowdStrike Falcon logo

CrowdStrike Falcon

Custom quote · Cloud

CrowdStrike Falcon is the market leader in cloud-native endpoint protection — strongest threat intelligence and detection rates — but premium pricing and the July 2024 outage incident are legitimate evaluation factors.

View profileContact vendor for exact pricing and packaging details.
CylancePROTECT logo

CylancePROTECT

Custom quote · Cloud

CylancePROTECT (now BlackBerry) was a pioneer in AI-based prevention but has lost momentum — the platform hasnt kept pace with CrowdStrike and SentinelOne, and BlackBerrys security business future is uncertain.

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ESET Protect logo

ESET Protect

Custom quote · Cloud / On-prem · Free trial

ESET PROTECT is a lightweight endpoint protection platform with the lowest system impact in the category — ideal for organizations with older hardware or performance-sensitive environments.

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Ivanti Neurons logo

Ivanti Neurons

Custom quote · Cloud / On-prem

Ivanti Neurons is positioned here as a endpoint management software option for teams comparing rollout fit, operating model, pricing structure, and how much administrative effort the product is likely to create after implementation.

View profileContact vendor for exact pricing and packaging details.
Malwarebytes ThreatDown logo

Malwarebytes ThreatDown

Per-endpoint · Cloud · Free trial

Malwarebytes ThreatDown (rebranded business product) is the simplest endpoint protection to deploy and manage — ideal for IT generalists who need effective protection without security expertise.

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ManageEngine Endpoint Central logo

ManageEngine Endpoint Central

Custom quote · Cloud / On-prem · Free trial

ManageEngine Endpoint Central is positioned here as a endpoint management software option for teams comparing rollout fit, operating model, pricing structure, and how much administrative effort the product is likely to create after implementation.

View profileContact vendor for exact pricing and packaging details.
Microsoft Defender for Endpoint logo

Microsoft Defender for Endpoint

Custom quote · Cloud

Microsoft Defender for Endpoint is the most cost-effective enterprise endpoint protection for Microsoft-heavy environments — included in M365 E5 — but detection depth and cross-platform coverage lag behind CrowdStrike and SentinelOne.

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SentinelOne Singularity logo

SentinelOne Singularity

Custom quote · Cloud

SentinelOne Singularity is the strongest autonomous endpoint protection platform — AI-driven detection and response with automated remediation — and the most credible CrowdStrike alternative for enterprises.

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Sophos Intercept X logo

Sophos Intercept X

Custom quote · Cloud · Free trial

Sophos Intercept X pairs strong endpoint protection with managed detection and response (MDR) that small and mid-market security teams can actually use — strongest for organizations that lack a dedicated SOC.

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Symantec Endpoint Security logo

Symantec Endpoint Security

Custom quote · Cloud

Symantec Endpoint Security (Broadcom) maintains strong detection capabilities but Broadcoms acquisition gutted support, partner relationships, and product velocity — evaluate with caution.

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Trellix Endpoint Security logo

Trellix Endpoint Security

Custom quote · Cloud / On-prem

Trellix Endpoint Security (formerly McAfee Enterprise + FireEye) is a legacy endpoint platform undergoing platform consolidation — strongest for existing McAfee/FireEye customers, but new buyers have better options.

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Trend Micro Apex One logo

Trend Micro Apex One

Custom quote · Cloud / On-prem

Trend Micro Apex One is a mature endpoint protection platform with hybrid deployment flexibility — one of the few options offering genuine on-premises and cloud parity — but the UX lags behind cloud-native competitors.

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VMware Carbon Black Cloud logo

VMware Carbon Black Cloud

Custom quote · Cloud

VMware Carbon Black Cloud is positioned for VMware-centric enterprises — deep vSphere integration for workload protection — but Broadcoms acquisition has created pricing uncertainty and roadmap questions.

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For MSPs FAQ for endpoint protection software

What endpoint protection software features do MSPs need?

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Multi-tenant dashboards with per-client isolation, PSA integration (ConnectWise, Autotask, Halo), white-label portals, per-technician or per-endpoint pricing with volume discounts, automated alerting with NOC escalation, and reporting that doubles as client deliverables.

How should MSPs evaluate endpoint protection software pricing?

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Compare per-technician (unlimited endpoints) vs per-endpoint models. For MSPs managing 500+ endpoints with 2-3 technicians, per-technician pricing is almost always cheaper. Factor in PSA integration costs, add-on modules, and minimum commit requirements.

Can MSPs use the same endpoint protection software tools as internal IT?

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Some tools serve both markets (NinjaOne, Datto), but MSP-specific features like multi-tenancy, white-labeling, and PSA integration are usually only available in MSP-tier plans. Internal IT tools (Intune, SCCM) lack multi-tenant architecture entirely.

Continue researching endpoint protection software